The SH-PTP2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to protein tyrosine phosphatase non-receptor type 11, and PTPN11. This antibody recognizes Human, Mouse, and Rat antigen. The SH-PTP2 Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity